Ironman Reggie Wayne's ACL tear caps a costly day in NFL

Colts receiver Reggie Wayne reacts after sustaining a knee injury against the Broncos during second...

Colts receiver Reggie Wayne reacts after sustaining a knee injury against the Broncos during second half NFL action in Indianapolis on Sunday, Oct. 20, 2013. Wayne is out for the season (Brian Spurlock/USA TODAY Sports)

JOHN KRYK, QMI Agency

, Last Updated: 9:20 PM ET

Maybe it was morbidly appropriate that a celebrated NFL ironman was the last star player to be carted off on a particularly dark day of devastating NFL injuries.

After Jay Cutler, after Sam Bradford, after Lance Briggs, after Leon Hall, after Brian Cushing, and after Jermichael Finley, there was Reggie Wayne -- the Indianapolis Colts wide receiver who hadn't missed a game since entering the league as a rookie in 2001 -- crumpling to the Lucas Oil Stadium turf, with just over seven minutes left in Indy's 39-33 upset of the visiting Denver Broncos.

Andrew Luck had thrown him a low pass, and while reaching awkwardly for it Wayne tore his right ACL, an MRI confirmed on Monday.

Wayne, 34, is done for the year. But not for his career, Colts head coach Chuck Pagano vowed.

"He'll be back. I know how he's wired, I know what his DNA is, I know how he is a man," Pagano said.


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