1. Indianapolis Colts (1-1) at San Francisco 49ers (1-1)
If Indy’s Andrew Luck rips up the 49ers secondary, it’s San Francisco head coach Jim Harbaugh’s fault. He’s the one who recruited Luck to Stanford then coached him up there into the draft-phenom QB he became. If anyone knows how to frustrate Luck, though, it should be Harbaugh.
2. Atlanta Falcons (1-1) at Miami Dolphins (2-0)
Matt Ryan, beware. His security blanket, LT Sam Baker, has been ruled out of this one. The Dolphins pass rush -- led by Cameron Wake -- must be drooling at the prospect. RB Steven Jackson also is out for Atlanta, while WRs Roddy White (ankle) and Julio Jones (knee) were both limited in practice all week.