Boston Red Sox designated hitter David Ortiz charged the mound and threw a punch at Baltimore reliever Kevin Gregg during a flyout in the bottom of the eighth inning.
Ortiz, who had homered in Thursday's 10-4 win and also hit a three-run bomb in an eight-run opening frame Friday, was thrown inside to three times during his at-bat in the eighth with the Red Sox up 10-3.
Gregg's 2-0 pitch was at the belt and brushed back Ortiz, who took a slow walk toward the mound and was held back by home plate umpire Mike Estabrook and Orioles catcher Matt Wieters as the dugouts emptied.
Ortiz, though, got back in the box and then lifted a lazy fly ball to center field. As he was going to first, Gregg motioned with his glove and seemed to say something to Ortiz, who made his way from the first-base line toward the reliever. The two shoved each other and both missed punches just as the dugouts and bullpens emptied.
Ortiz and Gregg were ejected along with Red Sox catcher Jarrod Saltalamacchia and Orioles pitcher Jim Johnson.
The Red Sox won the game by the 10-3 final.